Yohimbine hydrochloride ( NSC 19509; NIH 9689; Yohimbe )

Catalog No. M15476 CAS No. 65-19-0

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Product Name

Yohimbine hydrochloride
Note

Research use only, not for human use.
Brief Description

Yohimbine hydrochloride is an alpha 2-adrenoreceptor antagonist, blocking the pre- and postsynaptic alpha-2 adrenoreceptors and causing an increased release of noradrenaline and dopamine.
Description

Yohimbine hydrochloride is an alpha 2-adrenoreceptor antagonist, blocking the pre- and postsynaptic alpha-2 adrenoreceptors and causing an increased release of noradrenaline and dopamine.
Synonyms

NSC 19509; NIH 9689; Yohimbe
Pathway

Endocrinology/Hormones
Target

Adrenergic Receptor
Recptor

α-adrenergic receptor
Research Area

Other Indications
Indication

——

CAS Number

65-19-0
Formula Weight

390.90
Molecular Formula

C21H27ClN2O3
Purity

>98%(HPLC)
Solubility

DMSO: 12 mg/mL warmed (30.69 mM)
SMILES

COC(=O)[C@H]1[C@H](CC[C@@H]2[C@@H]1C[C@H]3C4=C(CCN3C2)C5=CC=CC=C5N4)O
Chemical Name

methyl (1R,2S,4aR,13bS,14aS)-2-hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylate hydrochloride

1.Ernst E, et al. J Urol, 1998, 159(2), 433-436.

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